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Use of cytokine immunotherapy to block CNS demyelination induced by a recombinant HSV-1 expressing IL-2
We previously have described a model of MS in which constitutive expression of murine IL-2 by HSV-1 (HSV-IL-2) causes CNS demyelination in different strains of mice (Zandian et al 2009, IOVS, 50:3275). In the current study, we investigated whether this HSV-IL-2-induced demyelination can be blocked u...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3118258/ https://ncbi.nlm.nih.gov/pubmed/21412284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2011.32 |
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