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Elevated serum IGF‐1 levels synergize PTH action on the skeleton only when the tissue IGF‐1 axis is intact

There is growing evidence that insulin‐like growth factor 1 (IGF‐1) and parathyroid hormone (PTH) have synergistic actions on bone and that part of the anabolic effects of PTH is mediated by local production of IGF‐1. In this study we analyzed the skeletal response to PTH in mouse models with manipu...

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書誌詳細
主要な著者: Elis, Sebastien, Courtland, Hayden‐William, Wu, Yingjie, Fritton, J Christopher, Sun, Hui, Rosen, Clifford J, Yakar, Shoshana
フォーマット: Artigo
言語:Inglês
出版事項: Wiley Subscription Services, Inc., A Wiley Company 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118256/
https://ncbi.nlm.nih.gov/pubmed/20499370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.100
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