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Identification of a novel temperature sensitive promoter in cho cells

BACKGROUND: The Chinese hamster ovary (CHO) expression system is the leading production platform for manufacturing biopharmaceuticals for the treatment of numerous human diseases. Efforts to optimize the production process also include the genetic construct encoding the therapeutic gene. Here we rep...

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Autors principals: Thaisuchat, Haruthai, Baumann, Martina, Pontiller, Jens, Hesse, Friedemann, Ernst, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118111/
https://ncbi.nlm.nih.gov/pubmed/21569433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-51
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