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Identification of a novel temperature sensitive promoter in cho cells

BACKGROUND: The Chinese hamster ovary (CHO) expression system is the leading production platform for manufacturing biopharmaceuticals for the treatment of numerous human diseases. Efforts to optimize the production process also include the genetic construct encoding the therapeutic gene. Here we rep...

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Detalhes bibliográficos
Main Authors: Thaisuchat, Haruthai, Baumann, Martina, Pontiller, Jens, Hesse, Friedemann, Ernst, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118111/
https://ncbi.nlm.nih.gov/pubmed/21569433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-51
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