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Estimating Extrinsic Dyes for Fluorometric Online Monitoring of Antibody Aggregation in CHO Fed-Batch Cultivations
Multi-wavelength fluorescence spectroscopy was evaluated in this work as tool for real-time monitoring of antibody aggregation in CHO fed-batch cultivations via partial least square (PLS) modeling. Therefore, we used the extrinsic fluorescence dyes 1-anilinonaphthalene-8-sulfonate (ANS), 4,4′-bis-1-...
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Publicado no: | Bioengineering (Basel) |
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Principais autores: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5615311/ https://ncbi.nlm.nih.gov/pubmed/28952544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering4030065 |
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