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Artificially designed promoters: Understanding the role of spatial features and canonical binding sites in transcription
The promoter is a key element in gene transcription and regulation. We previously reported that artificial sequences rich in the dinucleotide CpG are sufficient to drive expression in vitro in mammalian cell lines, without requiring canonical binding sites for transcription factor proteins. Here, we...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3357332/ https://ncbi.nlm.nih.gov/pubmed/22095054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bbug.18530 |
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