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Hydrogen Bonding Penalty upon Ligand Binding

Ligand binding involves breakage of hydrogen bonds with water molecules and formation of new hydrogen bonds between protein and ligand. In this work, the change of hydrogen bonding energy in the binding process, namely hydrogen bonding penalty, is evaluated with a new method. The hydrogen bonding pe...

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Autori principali: Zhao, Hongtao, Huang, Danzhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117785/
https://ncbi.nlm.nih.gov/pubmed/21698148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019923
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