Enthalpy of hydrogen bond formation in a protein-ligand binding reaction.

Parallel measurements of the thermodynamics (free-energy, enthalpy, entropy and heat-capacity changes) of ligand binding to FK506 binding protein (FKBP-12) in H2O and D2O have been performed in an effort to probe the energetic contributions of single protein-ligand hydrogen bonds formed in the bindi...

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Detalhes bibliográficos
Main Authors: Connelly, P R, Aldape, R A, Bruzzese, F J, Chambers, S P, Fitzgibbon, M J, Fleming, M A, Itoh, S, Livingston, D J, Navia, M A, Thomson, J A
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC43285/
https://ncbi.nlm.nih.gov/pubmed/7510408
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