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Regulation of protein-ligand binding affinity by hydrogen bond pairing

Hydrogen (H)-bonds potentiate diverse cellular functions by facilitating molecular interactions. The mechanism and the extent to which H-bonds regulate molecular interactions are a largely unresolved problem in biology because the H-bonding process continuously competes with bulk water. This interfe...

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Detaylı Bibliyografya
Yayımlandı:Sci Adv
Asıl Yazarlar: Chen, Deliang, Oezguen, Numan, Urvil, Petri, Ferguson, Colin, Dann, Sara M., Savidge, Tor C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Association for the Advancement of Science 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820369/
https://ncbi.nlm.nih.gov/pubmed/27051863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1501240
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