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Regulation of protein-ligand binding affinity by hydrogen bond pairing
Hydrogen (H)-bonds potentiate diverse cellular functions by facilitating molecular interactions. The mechanism and the extent to which H-bonds regulate molecular interactions are a largely unresolved problem in biology because the H-bonding process continuously competes with bulk water. This interfe...
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| Publié dans: | Sci Adv |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Association for the Advancement of Science
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4820369/ https://ncbi.nlm.nih.gov/pubmed/27051863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1501240 |
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