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LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activation
The ubiquitous Epstein Barr virus (EBV) exploits human B-cell development to establish a persistent infection in ∼90% of the world population. Constitutive activation of NF-κB by the viral oncogene latent membrane protein 1 (LMP1) has an important role in persistence, but is a risk factor for EBV-as...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117644/ https://ncbi.nlm.nih.gov/pubmed/21527913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.123 |
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