Functional delivery of viral miRNAs via exosomes

Noncoding regulatory microRNAs (miRNAs) of cellular and viral origin control gene expression by repressing the translation of mRNAs into protein. Interestingly, miRNAs are secreted actively through small vesicles called “exosomes” that protect them from degradation by RNases, suggesting that these m...

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Detalhes bibliográficos
Main Authors: Pegtel, D. Michiel, Cosmopoulos, Katherine, Thorley-Lawson, David A., van Eijndhoven, Monique A. J., Hopmans, Erik S., Lindenberg, Jelle L., de Gruijl, Tanja D., Würdinger, Thomas, Middeldorp, Jaap M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851954/
https://ncbi.nlm.nih.gov/pubmed/20304794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914843107
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