Functional delivery of viral miRNAs via exosomes

Noncoding regulatory microRNAs (miRNAs) of cellular and viral origin control gene expression by repressing the translation of mRNAs into protein. Interestingly, miRNAs are secreted actively through small vesicles called “exosomes” that protect them from degradation by RNases, suggesting that these m...

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Bibliographic Details
Main Authors: Pegtel, D. Michiel, Cosmopoulos, Katherine, Thorley-Lawson, David A., van Eijndhoven, Monique A. J., Hopmans, Erik S., Lindenberg, Jelle L., de Gruijl, Tanja D., Würdinger, Thomas, Middeldorp, Jaap M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851954/
https://ncbi.nlm.nih.gov/pubmed/20304794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914843107
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