Functional delivery of viral miRNAs via exosomes

Noncoding regulatory microRNAs (miRNAs) of cellular and viral origin control gene expression by repressing the translation of mRNAs into protein. Interestingly, miRNAs are secreted actively through small vesicles called “exosomes” that protect them from degradation by RNases, suggesting that these m...

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Bibliographische Detailangaben
Hauptverfasser: Pegtel, D. Michiel, Cosmopoulos, Katherine, Thorley-Lawson, David A., van Eijndhoven, Monique A. J., Hopmans, Erik S., Lindenberg, Jelle L., de Gruijl, Tanja D., Würdinger, Thomas, Middeldorp, Jaap M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851954/
https://ncbi.nlm.nih.gov/pubmed/20304794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914843107
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