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Exosomal sorting of the viral oncoprotein LMP1 is restrained by TRAF2 association at signalling endosomes
The Epstein–Barr virus (EBV)-encoded oncoprotein latent membrane protein 1 (LMP1) constitutively activates nuclear factor κB (NFκB) from intracellular membranes to promote cell growth and survival. LMP1 associates with CD63 in intracellular membranes and is released via exosomes. Whether tumour necr...
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| Publicado no: | J Extracell Vesicles |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Co-Action Publishing
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4394166/ https://ncbi.nlm.nih.gov/pubmed/25865256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3402/jev.v4.26334 |
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