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Synthetic and Immunological Studies of sTn Derivatives Carrying Substituted Phenylacetylsialic Acids as Cancer Vaccine Candidate

[Image: see text] To search for effective cancer vaccines based on sTn, a sialylated tumor-associated carbohydrate antigen (sialo-TACA) expressed by a number of tumors, four unnatural N-acyl sTn derivatives, including 5′-N-p-methylphenylacetyl sTn (sTnNMePhAc), 5′-N-p-methoxylphenylacetyl sTn (sTnNM...

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Detalhes bibliográficos
Main Authors: Wang, Qianli, Guo, Zhongwu
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2011
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117616/
https://ncbi.nlm.nih.gov/pubmed/21691430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100313d
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