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Improving the Antigenicity of sTn antigen by Modification of Its Sialic Acid Residue for Development of Glycoconjugate Cancer Vaccines
Sialyl Tn (sTn) antigen is a sialylated disaccharide abundantly expressed by many tumors. To search for effective cancer immunotherapies based on sTn antigen, this work designed and synthesized a series of unnatural N-acyl derivatives of sTn and studied their immunological property. For this purpose...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2006
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2532825/ https://ncbi.nlm.nih.gov/pubmed/17105234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc060103s |
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