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Synthesis and Evaluation of Protein Conjugates of GM3 Derivatives Carrying Modified Sialic Acids as Highly Immunogenic Cancer Vaccine Candidates

GM3, a sialylated trisaccharide antigen expressed by a number of tumors, is an attractive target in the design of therapeutic cancer vaccines. However, a serious problem associated with GM3 is that it is poorly immunogenic. To overcome this problem for the development of GM3-based cancer vaccines, f...

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書目詳細資料
Main Authors: Yu, Shichong, Wang, Qianli, Zhang, Junping, Wu, Qiuye, Guo, Zhongwu
格式: Artigo
語言:Inglês
出版: 2011
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172705/
https://ncbi.nlm.nih.gov/pubmed/21927709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C1MD00033K
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