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Synthesis and Evaluation of Protein Conjugates of GM3 Derivatives Carrying Modified Sialic Acids as Highly Immunogenic Cancer Vaccine Candidates

GM3, a sialylated trisaccharide antigen expressed by a number of tumors, is an attractive target in the design of therapeutic cancer vaccines. However, a serious problem associated with GM3 is that it is poorly immunogenic. To overcome this problem for the development of GM3-based cancer vaccines, f...

詳細記述

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書誌詳細
主要な著者: Yu, Shichong, Wang, Qianli, Zhang, Junping, Wu, Qiuye, Guo, Zhongwu
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172705/
https://ncbi.nlm.nih.gov/pubmed/21927709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C1MD00033K
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