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Synthesis and Immunological Properties of N-Modified GM3 Antigens as Therapeutic Cancer Vaccines
The problem of immunotolerance to GM3, an important tumor-associated trisaccharide antigen, seriously hinders its usage in cancer vaccine development. To solve this problem, the keyhole limpet hemocyanin (KLH) conjugates of a series of GM3 derivatives were synthesized and screened as therapeutic can...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3180873/ https://ncbi.nlm.nih.gov/pubmed/15689172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0494422 |
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