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Synthesis and Immunological Properties of N-Modified GM3 Antigens as Therapeutic Cancer Vaccines
The problem of immunotolerance to GM3, an important tumor-associated trisaccharide antigen, seriously hinders its usage in cancer vaccine development. To solve this problem, the keyhole limpet hemocyanin (KLH) conjugates of a series of GM3 derivatives were synthesized and screened as therapeutic can...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2005
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3180873/ https://ncbi.nlm.nih.gov/pubmed/15689172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm0494422 |
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