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Efficient Metabolic Engineering of GM3 on Tumor Cells by N-Phenylacetyl-D-mannosamine

Abnormal carbohydrates expressed on tumor cells, which are referred to as tumor-associated carbohydrate antigens (TACAs), are potential targets for development of cancer vaccines. However, immune tolerance to TACAs has severely hindered progress in this area. To overcome this problem, we have develo...

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Bibliografiske detaljer
Main Authors: Chefalo, Peter, Pan, Yanbin, Nagy, Nancy, Guo, Zhongwu, Harding, Clifford V.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531244/
https://ncbi.nlm.nih.gov/pubmed/16533056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi052161r
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