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Efficient Metabolic Engineering of GM3 on Tumor Cells by N-Phenylacetyl-D-mannosamine

Abnormal carbohydrates expressed on tumor cells, which are referred to as tumor-associated carbohydrate antigens (TACAs), are potential targets for development of cancer vaccines. However, immune tolerance to TACAs has severely hindered progress in this area. To overcome this problem, we have develo...

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Detalles Bibliográficos
Main Authors: Chefalo, Peter, Pan, Yanbin, Nagy, Nancy, Guo, Zhongwu, Harding, Clifford V.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531244/
https://ncbi.nlm.nih.gov/pubmed/16533056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi052161r
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