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Efficient Metabolic Engineering of GM3 on Tumor Cells by N-Phenylacetyl-D-mannosamine

Abnormal carbohydrates expressed on tumor cells, which are referred to as tumor-associated carbohydrate antigens (TACAs), are potential targets for development of cancer vaccines. However, immune tolerance to TACAs has severely hindered progress in this area. To overcome this problem, we have develo...

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Autori principali: Chefalo, Peter, Pan, Yanbin, Nagy, Nancy, Guo, Zhongwu, Harding, Clifford V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531244/
https://ncbi.nlm.nih.gov/pubmed/16533056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi052161r
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