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Isolating Toxic Insulin Amyloid Reactive Species that Lack β-Sheets and Have Wide pH Stability
Amyloid diseases, including Alzheimer's disease, are characterized by aggregation of normally functioning proteins or peptides into ordered, β-sheet rich fibrils. Most of the theories on amyloid toxicity focus on the nuclei or oligomers in the fibril formation process. The nuclei and oligomers...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3117171/ https://ncbi.nlm.nih.gov/pubmed/21641325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.04.046 |
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