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Mechanisms for the Evolution of a Derived Function in the Ancestral Glucocorticoid Receptor
Understanding the genetic, structural, and biophysical mechanisms that caused protein functions to evolve is a central goal of molecular evolutionary studies. Ancestral sequence reconstruction (ASR) offers an experimental approach to these questions. Here we use ASR to shed light on the earliest fun...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3116920/ https://ncbi.nlm.nih.gov/pubmed/21698144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002117 |
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