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Deciphering Modern Glucocorticoid Cross-pharmacology Using Ancestral Corticosteroid Receptors
Steroid receptors (SRs) are the largest family of metazoan transcription factors and control genes involved in development, endocrine signaling, reproduction, immunity, and cancer. The entire hormone receptor system is driven by a molecular switch triggered by the binding of small lipophilic ligands...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3351298/ https://ncbi.nlm.nih.gov/pubmed/22437833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.346411 |
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