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Glucocorticoid receptor condensates link DNA-dependent receptor dimerization and transcriptional transactivation

The glucocorticoid receptor (GR) is a ligand-regulated transcription factor (TF) that controls the tissue- and gene-specific transactivation and transrepression of thousands of target genes. Distinct GR DNA-binding sequences with activating or repressive activities have been identified, but how they...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Frank, Filipp, Liu, Xu, Ortlund, Eric A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8325269/
https://ncbi.nlm.nih.gov/pubmed/34285072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2024685118
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