Clinical-Grade Generation of Active NK Cells from Cord Blood Hematopoietic Progenitor Cells for Immunotherapy Using a Closed-System Culture Process

Natural killer (NK) cell-based adoptive immunotherapy is a promising treatment approach for many cancers. However, development of protocols that provide large numbers of functional NK cells produced under GMP conditions are required to facilitate clinical studies. In this study, we translated our cy...

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Detalhes bibliográficos
Main Authors: Spanholtz, Jan, Preijers, Frank, Tordoir, Marleen, Trilsbeek, Carel, Paardekooper, Jos, de Witte, Theo, Schaap, Nicolaas, Dolstra, Harry
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116834/
https://ncbi.nlm.nih.gov/pubmed/21698239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020740
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