MMP-2 siRNA Inhibits Radiation-Enhanced Invasiveness in Glioma Cells

BACKGROUND: Our previous work and that of others strongly suggests a relationship between the infiltrative phenotype of gliomas and the expression of MMP-2. Radiation therapy, which represents one of the mainstays of glioma treatment, is known to increase cell invasion by inducing MMP-2. Thus, inhib...

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Bibliographic Details
Main Authors: Badiga, Aruna Venkata, Chetty, Chandramu, Kesanakurti, Divya, Are, Deepthi, Gujrati, Meena, Klopfenstein, Jeffrey D., Dinh, Dzung H., Rao, Jasti S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116828/
https://ncbi.nlm.nih.gov/pubmed/21698233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020614
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