An unliganded thyroid hormone receptor causes severe neurological dysfunction

Congenital hypothyroidism and the thyroid hormone (T(3)) resistance syndrome are associated with severe central nervous system (CNS) dysfunction. Because thyroid hormones are thought to act principally by binding to their nuclear receptors (TRs), it is unexplained why TR knock-out animals are report...

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Podrobná bibliografie

Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Hashimoto, Koshi, Curty, Flavio H., Borges, Patricia P., Lee, Charlotte E., Abel, E. Dale, Elmquist, Joel K., Cohen, Ronald N., Wondisford, Fredric E.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 2001
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31168/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11274423/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.051454698
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