An unliganded thyroid hormone receptor causes severe neurological dysfunction
Congenital hypothyroidism and the thyroid hormone (T(3)) resistance syndrome are associated with severe central nervous system (CNS) dysfunction. Because thyroid hormones are thought to act principally by binding to their nuclear receptors (TRs), it is unexplained why TR knock-out animals are report...
Salvato in:
| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31168/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11274423/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.051454698 |
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