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eIF5 is a dual function GAP and GDI for eukaryotic translational control

We recently showed in a publication in Nature that the eukaryotic translation initiation factor eIF5 has a second regulatory function and is a GDI (GDP dissociation inhibitor) in addition to its previously characterized role as a GAP (GTPase accelerating protein). These findings provide new insight...

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Bibliografiske detaljer
Main Authors: Jennings, Martin D, Pavitt, Graham D
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116597/
https://ncbi.nlm.nih.gov/pubmed/21686265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.1.2.13783
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