Polymorphisms of MDM4 and risk of squamous cell carcinoma of the head and neck

PURPOSE: Mouse double minute 4 (MDM4), a homolog of MDM2, is a key negative regulator of p53, and its amplification or over-expression contributes to carcinogenesis by inhibiting the p53 tumor suppressor activity. We investigated the association between MDM4 polymorphisms and risk of squamous cell c...

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Main Authors: Yu, Hongping, Wang, Li-E, Zhensheng, Liu, Wei, Sheng, Li, Guojun, Sturgis, Erich M., Wei, Qingyi
格式: Artigo
語言:Inglês
出版: 2011
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116079/
https://ncbi.nlm.nih.gov/pubmed/21540763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32834632e4
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