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Modifying effect of MDM4 variants on risk of HPV16-associated squamous cell carcinoma of oropharynx
BACKGROUND: The p53 pathway plays a critical role in maintaining genomic stability and preventing tumor formation. Given the roles of both MDM4 and HPV16 E6 oncoproteins in inhibition of p53 activity, we tested the hypothesis that MDM4 polymorphisms are associated with the risk of HPV16-associated s...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3213304/ https://ncbi.nlm.nih.gov/pubmed/21823114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26423 |
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