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Catecholamine-Independent Heart Rate Increases Require CaMKII
BACKGROUND: Catecholamines increase heart rate by augmenting the cAMP responsive HCN4 ‘pacemaker current’ (I(f)) and/or by promoting inward Na(+)/Ca(2+) exchanger current (I(NCX)), by a ‘Ca(2+) clock’ mechanism in sinoatrial nodal cells (SANCs). The importance, identity and function of signals that...
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| Autors principals: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3116039/ https://ncbi.nlm.nih.gov/pubmed/21406683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.110.961771 |
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