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Isolation of viable antigen-specific CD8(+) T cells based on membrane-bound tumor necrosis factor (TNF)-α expression

Current technology to isolate viable cytokine-producing antigen-specific primary human T cells is limited to bi-specific antibody capture systems, which suffer from limited sensitivity and high background. Here, we describe a novel procedure for isolating antigen-specific human T cells based on thei...

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Detalhes bibliográficos
Main Authors: Haney, Danielle, Quigley, Maire F., Asher, Tedi E., Ambrozak, David R., Gostick, Emma, Price, David A., Douek, Daniel C., Betts, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116017/
https://ncbi.nlm.nih.gov/pubmed/21501617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2011.04.003
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