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Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8(+) T-Cell Population in Elite Controllers

During chronic human immunodeficiency virus (HIV) infection, virus-specific CD8(+) T cells become functionally exhausted. Unlike most chronically infected individuals, elite controllers of HIV retain CD8(+) T-cell polyfunctionality and cytolytic capacity. It remains unclear whether elite controllers...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Pombo, Carolina, Wherry, E. John, Gostick, Emma, Price, David A., Betts, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601914/
https://ncbi.nlm.nih.gov/pubmed/25883386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv226
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