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Direct Measurement of Cathepsin B Activity in the Cytosol of Apoptotic Cells by an Activity-Based Probe

Cells control their own death through a program termed apoptosis, which is indispensable for development and homeostasis in all metazoans. Lysosomal cysteine proteases are not normally thought of as participating in apoptosis; however, recent reports have shown that the cathepsin proteases can be re...

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Autors principals: Pratt, Matthew R., Sekedat, Matthew D., Chiang, Kyle P., Muir, Tom W.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115634/
https://ncbi.nlm.nih.gov/pubmed/19778728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.07.011
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