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Generation of hematopoietic humanized mice in the newborn BALB/c-Rag2(null)Il2rγ(null) mouse model: a multivariable optimization approach

Hematopoietic humanized mice generated via transplantation of human hematopoietic stem cells (hHSCs) into immunodeficient mice are a valuable tool for studying development and function of the human immune system. This study was performed to generate a protocol that improves development and quality o...

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Detalhes bibliográficos
Main Authors: Lang, Julie, Weiss, Nicholas, Freed, Brian M., Torres, Raul M., Pelanda, Roberta
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115423/
https://ncbi.nlm.nih.gov/pubmed/21536497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2011.04.002
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