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The Molecular Basis of N-end Rule Recognition

The N-end rule targets specific proteins for destruction in prokaryotes and eukaryotes. Here, we report a crystal structure of a bacterial N-end rule adaptor, ClpS, bound to a peptide mimic of an N-end rule substrate. This structure, which was solved at a resolution of 1.15 Å, reveals specific recog...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Kevin H., Roman-Hernandez, Giselle, Grant, Robert A., Sauer, Robert T., Baker, Tania A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114436/
https://ncbi.nlm.nih.gov/pubmed/18995838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.08.032
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