Diazoxide-Unresponsive Congenital Hyperinsulinism in Children With Dominant Mutations of the β-Cell Sulfonylurea Receptor SUR1

OBJECTIVE: Congenital hyperinsulinemic hypoglycemia is a group of genetic disorders of insulin secretion most commonly associated with inactivating mutations of the β-cell ATP-sensitive K(+) channel (K(ATP) channel) genes ABCC8 (SUR1) and KCNJ11 (Kir6.2). Recessive mutations of these genes cause hyp...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: MacMullen, Courtney M., Zhou, Qing, Snider, Kara E., Tewson, Paul H., Becker, Susan A., Aziz, Ali Rahim, Ganguly, Arupa, Shyng, Show-Ling, Stanley, Charles A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Diabetes Association 2011
Ämnen:
Genetics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114386/
https://ncbi.nlm.nih.gov/pubmed/21536946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1631
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk