Clinical characteristics and biochemical mechanisms of congenital hyperinsulinism associated with dominant K(ATP )channel mutations

Congenital hyperinsulinism is a condition of dysregulated insulin secretion often caused by inactivating mutations of the ATP-sensitive K(+) (K(ATP)) channel in the pancreatic β cell. Though most disease-causing mutations of the 2 genes encoding K(ATP) subunits, ABCC8 (SUR1) and KCNJ11 (Kir6.2), are...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Pinney, Sara E., MacMullen, Courtney, Becker, Susan, Lin, Yu-Wen, Hanna, Cheryl, Thornton, Paul, Ganguly, Arupa, Shyng, Show-Ling, Stanley, Charles A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441858/
https://ncbi.nlm.nih.gov/pubmed/18596924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35414
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares