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Substrate recognition and selectivity in the type IC DNA modification methylase M.EcoR124I.

The type I DNA modification methylase M.EcoR124I binds sequence specifically to DNA and protects a 25bp fragment containing its cognate recognition sequence from digestion by exonuclease III. Using modified synthetic oligonucleotide duplexes we have investigated the catalytic properties of the methy...

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Autori principali: Taylor, I, Watts, D, Kneale, G
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1993
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC311408/
https://ncbi.nlm.nih.gov/pubmed/8177741
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