Non-Apical Membrane Antigen 1 (AMA1) IgGs from Malian Children Interfere with Functional Activity of AMA1 IgGs as Judged by Growth Inhibition Assay

BACKGROUND: Apical membrane antigen 1 (AMA1) is one of the best-studied blood-stage malaria vaccine candidates. When an AMA1 vaccine was tested in a malaria naïve population, it induced functionally active antibodies judged by Growth Inhibition Assay (GIA). However, the same vaccine failed to induce...

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Detalhes bibliográficos
Main Authors: Miura, Kazutoyo, Perera, Suwani, Brockley, Sarah, Zhou, Hong, Aebig, Joan A., Moretz, Samuel E., Miller, Louis H., Doumbo, Ogobara K., Sagara, Issaka, Dicko, Alassane, Ellis, Ruth D., Long, Carole A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113848/
https://ncbi.nlm.nih.gov/pubmed/21695140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020947
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