A Randomized, Controlled, Phase 1 Study of the Safety and Immunogenicity of the AMA1-C1/Alhydrogel(®) + CPG 7909 Vaccine for Plasmodium falciparum Malaria, in Semi-immune Malian Adults

A double blind, randomized, controlled Phase 1 clinical trial was conducted to assess the safety and immunogenicity in malaria exposed adults of the Plasmodium falciparum blood stage vaccine candidate Apical Membrane Antigen 1- Combination 1 (AMA1-C1)/Alhydrogel(®) with and without the novel adjuvan...

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Hlavní autoři: Sagara, Issaka, Ellis, Ruth D., Dicko, Alassane, Niambele, Mohamed B., Kamate, Beh, Guindo, Ousmane, Sissoko, Mahamadou S., Fay, Michael P., Guindo, Merepen A., Kante, Ousmane, Saye, Renion, Miura, Kazutoyo, Long, Carole, Mullen, Gregory E.D., Pierce, Mark, Martin, Laura B., Rausch, Kelly, Dolo, Amagana, Diallo, Dapa A., Miller, Louis H, Doumbo, Ogobara K
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808270/
https://ncbi.nlm.nih.gov/pubmed/19874925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.10.087
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