A Randomized Controlled Phase 2 Trial of the Blood Stage AMA1-C1/Alhydrogel Malaria Vaccine in Children in Mali

A double blind, randomized, controlled Phase 2 clinical trial was conducted to assess the safety, immunogenicity, and biologic impact of the vaccine candidate Apical Membrane Antigen 1- Combination 1 (AMA1-C1), adjuvanted with Alhydrogel(®). Participants were healthy children 2-3 years old living in...

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Hlavní autoři: Sagara, Issaka, Dicko, Alassane, Ellis, Ruth D., Fay, Michael P., Diawara, Sory I., Assadou, Mahamadoun H., Sissoko, Mahamadou S., Kone, Mamady, Diallo, Abdoulbaki I., Saye, Renion, Guindo, Merepen A., Kante, Ousmane, Niambele, Mohamed B., Miura, Kazutoyo, Mullen, Gregory E.D., Pierce, Mark, Martin, Laura B., Dolo, Amagana, Diallo, Dapa A., Doumbo, Ogobara K, Miller, Louis H, Saul, Allan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713037/
https://ncbi.nlm.nih.gov/pubmed/19428923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.03.014
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