Phase 1 Study of a Combination AMA1 Blood Stage Malaria Vaccine in Malian Children

BACKGROUND: Apical Membrane Antigen-1 (AMA1) is one of the leading blood stage malaria vaccine candidates. AMA1-C1/Alhydrogel® consists of an equal mixture of recombinant AMA1 from FVO and 3D7 clones of P. falciparum, adsorbed onto Alhydrogel®. A Phase 1 study in semi-immune adults in Mali showed th...

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Hlavní autoři: Dicko, Alassane, Sagara, Issaka, Ellis, Ruth D., Miura, Kazutoyo, Guindo, Ousmane, Kamate, Beh, Sogoba, Moussa, Niambelé, Mohamed Balla, Sissoko, Mady, Baby, Mounirou, Dolo, Amagana, Mullen, Gregory E. D., Fay, Michael P., Pierce, Mark, Diallo, Dapa A., Saul, Allan, Miller, Louis H., Doumbo, Ogobara K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2216433/
https://ncbi.nlm.nih.gov/pubmed/18270560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001563
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