Aciculatin inhibits lipopolysaccharide-mediated inducible nitric oxide synthase and cyclooxygenase-2 expression via suppressing NF-κB and JNK/p38 MAPK activation pathways

OBJECTIVES: Natural products have played a significant role in drug discovery and development. Inflammatory mediators such as inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) have been suggested to connect with various inflammatory diseases. In this study, we explored the anti-inf...

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Main Authors: Hsieh, I-Ni, Chang, Anita Shin-Yuan, Teng, Che-Ming, Chen, Chien-Chih, Yang, Chia-Ron
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113733/
https://ncbi.nlm.nih.gov/pubmed/21548916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-18-28
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