IL-8 promotes inflammatory mediators and stimulates activation of p38 MAPK/ERK-NF-κB pathway and reduction of JNK in HNSCC

This investigation identifies interleukin 8 (IL-8) as the main inflammatory mediator in head and neck squamous cell carcinoma (HNSCC). The expressions of chemokines of IL-8, IL-1β and IL-6 and the cytokines of tumor necrosis factor-α (TNF-α) were higher in HNSCC patient tissues than in non-cancerous...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chan, Leong-Perng, Liu, Cheng, Chiang, Feng-Yu, Wang, Ling-Feng, Lee, Ka-Wo, Chen, Wan-Ting, Kuo, Po-Lin, Liang, Chia-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593568/
https://ncbi.nlm.nih.gov/pubmed/28915597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16914
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