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Increased sensitivity to TNF-α promotes keloid fibroblast hyperproliferation by activating the NF-κB, JNK and p38 MAPK pathways

Hyperproliferation of fibroblasts is the main cause of keloid formation. However, the pathogenesis of keloids has yet to be fully elucidated. Tumor necrosis factor (TNF)-α may play an important role in the formation and proliferation of keloids, as it is implicated in the pathogenesis of various fib...

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Vydáno v:Exp Ther Med
Hlavní autoři: Li, Qijie, Cheng, Fengrui, Zhou, Kai, Fang, Lu, Wu, Junliang, Xia, Qingjie, Cen, Ying, Chen, Junjie, Qing, Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005672/
https://ncbi.nlm.nih.gov/pubmed/33791011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2021.9933
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