Inhibition of cathepsin S confers sensitivity to methyl protodioscin in oral cancer cells via activation of p38 MAPK/JNK signaling pathways

Oral cancer is one of the most common cancers in the world. Approximately 90% of oral cancers are subtyped to oral squamous cell carcinoma (OSCC). Despite advances in diagnostic techniques and improvement in treatment modalities, the prognosis remains poor. Therefore, an effective chemotherapy mecha...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Hsieh, Ming-Ju, Lin, Chiao-Wen, Chen, Mu-Kuan, Chien, Su-Yu, Lo, Yu-Sheng, Chuang, Yi-Ching, Hsi, Yi-Ting, Lin, Chia-Chieh, Chen, Jui-Chieh, Yang, Shun-Fa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361207/
https://ncbi.nlm.nih.gov/pubmed/28327651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45039
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