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Understanding and predicting synthetic lethal genetic interactions in Saccharomyces cerevisiae using domain genetic interactions

BACKGROUND: Synthetic lethal genetic interactions among proteins have been widely used to define functional relationships between proteins and pathways. However, the molecular mechanism of synthetic lethal genetic interactions is still unclear. RESULTS: In this study, we demonstrated that yeast synt...

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Hlavní autoři: Li, Bo, Cao, Weiguo, Zhou, Jizhong, Luo, Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113237/
https://ncbi.nlm.nih.gov/pubmed/21586150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-73
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