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Understanding and predicting synthetic lethal genetic interactions in Saccharomyces cerevisiae using domain genetic interactions

BACKGROUND: Synthetic lethal genetic interactions among proteins have been widely used to define functional relationships between proteins and pathways. However, the molecular mechanism of synthetic lethal genetic interactions is still unclear. RESULTS: In this study, we demonstrated that yeast synt...

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Detalhes bibliográficos
Main Authors: Li, Bo, Cao, Weiguo, Zhou, Jizhong, Luo, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113237/
https://ncbi.nlm.nih.gov/pubmed/21586150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-73
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